Bosentan Ip/Ep/Bp/Usp Cas No: 147536-97-8

BOSENTAN IP/EP/BP/USP

Brand Name: BOSENTAN
250000.00 INR / Kilograms (250000.00 INR + 0% GST)
  • 1 Pack Contains: 1
  • Minimum Pack Size: 1

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Niksan Pharmaceutical

9 Years Member Since : 9 Years
Mr Sanjay Patel
Ankleshwar, Gujarat ...More Plot No. 4706/03, Gidc Estate, SF-12, Shrinathji Arcade, Near Meghmani Chowkadi, Ankleshwar, Gujarat, 393002, India

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Product Details

Unit of MeasureKilograms/Kilograms
Unit of PriceKilograms/Kilograms
Moq1
Chemical NameBosentan
Molecular FormulaC27H29N5O6S
Molecular Weight551.61 ga cmol a 1
Shelf Life3 Years
Loss on Drying1 %
GradeMedicine Grade
UsageANTIHYPERTENSIVE
Physical FormPowder
CAS No147536-97-8
AppearanceWHITE
TasteOdorless
Medicine NameBosentan Monohydrate
Particle SizeD90LESS THAN 10 MICRON
StorageKeep away from moisture
SmellStimulus
Purity(%)99
TypeCardiovascular Agents
Sample PolicyWithin a certain price range free samples are available
Supply Ability10 KG Per Month
Sample AvailableYES
Main Domestic MarketAll India, North India, South India, Central India, East India
Delivery Time15 Days
FOB PortSAHAR AIR CARGO
Packaging DetailsHDPE drum with inner LPDE liners
CertificationsFDCA, GMP, GLP and ISO
GSTIN0%
ReturnableNo
Brand NameBOSENTAN
Product Unit1Kilograms/Kilograms
Unit TypeKilograms/Kilograms
CurrencyINR
Packsize1
Stock Quantity10
price_typefixed
Product Description

Niksan Pharmaceutical is the largest manufacturer and exporter of the Bosentan API among all over the world. Niksan Pharmaceutical is one of biggest the supplier, manufacturer, exporter and distributor of the Bosentan API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.
Niksan Pharmaceutical provides API and finished formulations of Bosentan in all over Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Jammu Kashmir Etc.
Niksan pharmaceutical is also large exporter of the API and finished pharmaceutical products of Bosentan in many countries for years. The countries where we exporting are Colombia, Iraq, Paraguay, Switzerland, Argentina, Mexico, Pakistan, South Korea, Italy, Germany, Romania, Saudi Arabia, Philippines, Egypt, Spain, Portugal, Australia, United States, Tunisia , Canada, Iran, Turkey, Chile, United Kingdom, Taiwan, Austria, Netherlands, France, Belgium, Peru, Thailand, Venezuela, Vietnam, Poland, Brazil, Indonesia and many more countries.
Bosentan is the medicine used in the treatment of pulmonary artery hypertension.
Bosentan belongs to endothel in receptor antagonist. Bosentan increase blood flow in patient suffering from PAH.

SYNONYMS OF BOSENTAN: BosentA n, Bosentan, Bosentanum.

IUPAC NAME: 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2(pyrimidin-2-yl) pyrimidin-4-yl] benzene-1-sulfonamide

CAS NO: 147536-97-8

FORMULA: C27H29N5O6S

MOLECULAR MASS: 551.61 ga cmol a 1

STORAGE CONDITIONS: Store in cool and dry place, keep away from direct heat and light.Do not put in humid place like bathroom.Keep away from children and pet.

HOW TO USE:Take this medicine 2 times per day, normally in morning and evening.
Take medicines by mouth with or without water. Put you tablet in small amount of water and dissolve it, when it dissolves drink whole mixture at once.

HOW BOSENTAN WORKS: Bosentan used in the treatment of pulmonary artery hypertension.It blocks the effects of endothelin and by this Bosentan increase the blood flow in vessels and give relief in PAH (pulmonary artery hypertension)

PHARMACOKINETICS:Bosentan have very low solubility so Bosentan absorbed when it taken in high amount.The drug binds with almost 98% of plasma protein.Bioavaibility of this medicine is 505 and it is not affected by food.Half-life of Bosentan in health person is 5hrs.The Bosentan excited by the biliary excretion.

SIDE EFFECTS OF BOSENTAN: Runny nose, dizziness, flushing and joint pain are the common side effects seen in the patients.If you see symptoms like swelling of ankles, fainting, weight gain, shortness of breath, fast heartbeat, weakness tell your doctor about this problems.This drug can effects on sperm production and also affect your ability to become father.The allergic reaction of Bosentan is rare.

PRECAUTION:Tell your doctor if you have allergic reaction towards the Bosentan.
Talk with your doctor if you have other disease like liver or kidney problems.This rug cause dizziness so kindly avoid driving and heavy exercise.Consumption of alcohol or cannabis can make you dizzier so kindly avoid it while taking the medicament.If you must not be taken in pregnancy because it can harms the unborn baby.

CDSCO APPROVAL: Bosentan (as monohydrate) Tablets 62.5mg/125mg approved by CDSCO in Indian in 23.06.2009.

FORMULATIONS AVAAILABLE IN MARKET:
Bosentan 62.5mg tablets
Bosentan 125mg tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult

Company Details

NIKSAN PHARMACEUTICAL was established by a group of experienced professionals with an objective to develop Pharmaceutical Products in a complex quality driven atmosphere. we put in our the best efforts to provide Active Pharmaceutical Ingredients and Pharmaceutical Finished Formulation in various dosage forms (Tablets, Capsules, Syrups, Gels, Ointments, Nasal Sprays and Dry powder in pouch Pack) with prime focus on the exports of the APIs and Pharmaceutical Finished Formulation. We maintain high level of integrity and transparency in our business processes and dealings and thus assure high quality products to the customers. We are developing high quality Pharmaceutical Intermediate through Research & Development using new technologies. Our R & D team is expert Process Development, process optimization and scale-up to big quantity.

  • BUSINESS TYPE Exporter, Importer, Manufacturer, Supplier, Trading Company, Wholesaler, Dealer
  • EMPLOYEE COUNT 20
  • ESTABLISHMENT 2013
  • ANNUAL TURNOVER Rs 12 Crores
  • CERTIFICATION FIRM REGISTRATION
  • WORKING DAYS Sunday To Monday
  • PAYMENT MODE Cash Against Delivery (CAD), Cash on Delivery (COD), Cash Advance (CA), Cash in Advance (CID), Cheque, Days after Acceptance (DA), Delivery Point (DP), Letter of Credit (L/C), Letter of Credit at Sight (Sight L/C), Telegraphic Transfer (T/T), Western Union, Paypal, Others
  • GST NO 24AAKFN4352Q1ZR
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